Senior Python backend developer

CytoReason

CytoReason

Software Engineering
Tel Aviv-Yafo, Israel
Posted on Jan 18, 2026

Senior Python backend developer

  • R&D
  • Tel Aviv, Israel
  • Senior
  • Full-time

Description

We are seeking an experienced Senior Python Engineer to join our engineering team and drive the development of robust, scalable, and high-performance backend solutions. In this role, you will design and implement core services, optimize data workflows, and contribute to architecture decisions that support mission-critical applications. The ideal candidate brings deep expertise in Python, hands-on experience with distributed systems or data-intensive environments, and a passion for building reliable, production-grade software.

Responsibilities

  • Enabling the adoption of next-generation orchestration tool – Nextflow
  • Build software components to automate and reduce human work to annotate and design a model
  • Design and implement backend APIs using Nest.js,FastAPI integrating with data layers and external systems.
  • Contribute to and review frontend features in React, ensuring seamless integration with backend services.
  • Help design and shape the product, working closely with product managers, bioinformaticians, and other stakeholders to align technical decisions with product goals.
  • Mentor and support other developers through code reviews, internal discussions, clean code and technical guidance.
  • Collaborate cross-functionally with product, data, and infrastructure teams to define requirements and deliver solutions.
  • Write and maintain technical documentation and high-level designs

The Tech You’ll Work With:

  • Frontend: React, TypeScript, Tailwind CSS
  • Data & Storage: LakeFS, PostgreSQL, BigQuery
  • Cloud: Google Cloud Platform (GCP), AWS
  • Additional tools: Python, R (familiarity a plus, not required)
  • CI/CD & DevOps: Docker, Kubernetes

Requirements

  • 7+ years of experience as a full-stack or backend-focused developer with expereise in data releate product.
  • Proficiency in NodePython .js / Nest.js and experience with scalable API design.
  • Strong understanding of distributed systems, performance optimization, and cloud architectures.
  • Experience leading projects or mentoring engineers — you enjoy helping others grow.
  • Hands-on experience with modern frontend frameworks, preferably Reactin Python.
  • Strong communication and planning skills, with the ability to provide technical input during project scoping.
  • Track record of delivering efficiently in agile teams with shifting priorities.
  • Proactive mindset — someone who can take ownership, identify problems, and propose solutions.

Advantages

  • Experience with Python or R for data-related workflows.
  • Background in data-intensive systems or bioinformatics.
  • Hands-on experience with modern frontend frameworks, preferably React.
  • Familiarity with multi-cloud environments (GCP + AWS)